| Robert Spencer *1570-†1627 1st Lord Spencer of Wormleighton |
| Margareth Willoughby *1570-†1597 |
| Henry Wriothesley *1573-†1624 3th Earl of Southampton |
| Elisabeth Vernon of Hodnet *1580-†1655 |
| William Spencer *1592-†1636 of Wormleighton |
| Penelope Wriothesley *1598-†1667 |
| Henry Spencer *1620-†1643 1st Earl of Sunderland, 3rd Baron Spencer |
| Dorothy Sidney *1617-†1684 |
| Dorothy Spencer *1639-†1670 |
| Robert Spencer *1641-†1702 |